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Guide to Denosumab Injection in 2024

Medication Purpose and Use

Denosumab is a medication used to mitigate excessive bone loss. It's prescribed for increasing bone mass to prevent or treat conditions like osteoporosis, as well as managing bone pain associated with cancer. This medication typically comes in a prefilled syringe or vial format. 



Denosunab Injection can help with Osteoporosis

Recommended Dosage and Administration

Denosumab is administered via a subcutaneous injection into the upper arm, thigh, or abdomen. The frequency of injections varies, with some requiring it every 4 weeks and others every 6 months, based on individual needs. 


It's crucial to ensure an adequate intake of calcium (1000 mg/day) and vitamin D (400 units/day) while undergoing treatment with Denosumab.


If you miss a dose, please administer the injection as soon as you remember. If you have a medical concern or require clarifications, please talk to your doctor.

What are common side effects?

Common adverse effects of Denosumab include: 

  • pain in muscles, back, bones, and joints, 

  • elevated cholesterol levels, 

  • nausea or vomiting, 

  • constipation, 

  • and mild fatigue. 


Please inform your doctor if you experience any of the following:

  • Excessive muscle cramps,

  • Dizziness or confusion,

  • Excessive skin dryness, irritation, rashes or sores

  • Chest pain, discomfort or irregular heart beats

  • Fever, pain during urination, gum pain or bleeding gums

  • Severe nausea, vomiting, or abdominal pain.


The above are not an exhaustive source of symptoms. If you are unsure, please seek a doctor’s opinion.


What precautions should I take while on Denosumab?

  • Denosumab is available under two distinct brand names, Prolia® and Xgeva®. It is important not to switch between these brands without checking with your doctor first.


  • Maintain good oral hygiene and inform your dentist that you are undergoing Denosumab treatment, so that appropriate precautions can be taken. 


  • For females, please use effective birth control, and also inform your doctor if you intend to conceive or breastfeed.



Denosumab Price in Singapore

At Advantage Medical, we can provide denosumab injections at the following costs:

  • $575 per jab

  • $1100 for 2 jabs, spaced out by 6 monthly intervals


Prices are subject to GST.

Where can I get a Denosumab injection in Singapore?

Denosumab injection is available at all four clinics in Bedok, Bukit Timah, Geylang and Jurong West. Book an appointment with our friendly staff today through WhatsApp at 87840093.


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